This space-saving mouse includes the unifying receiver and runs on a AA battery for 18 months. You don’t need to move your arm and can manipulate the mouse with your thumb. Made with an exposed ball on the top and a sculpted shape, this mouse is comfortable to hold and control. A vertical mouse is better suited for the prevention of this neurological disorder.ġ. If you already have carpal tunnel syndrome or other disabilities but your tasks do not require high precision, consider a trackball. If you are a hardcore gamer or a graphic designer, opt for a vertical mouse. A trackball is a bit slower and less precise, therefore, it is not a good choice for certain types of games. A trackball mouse uses the thumb for movement and offers a more comfortable hold. This reduces hand fatigue and discomfort, preventing carpal tunnel from occurring. With a vertical mouse, you hold your hand vertically rather than laying it flat on the mouse. What is the best mouse for carpal tunnel? You have two options: a vertical mouse like the Logitech MX and a trackball mouse like the Logitech M570.